Semaglutide, a peptide-based medication, is administered through weekly injections. The treatment begins with a low dosage, which is gradually increased over a period of 16 weeks to achieve the optimal dose necessary for effective weight loss. This incremental increase is designed to allow the body to adjust to the medication and to minimize potential side effects.

One of the key mechanisms by which semaglutide aids in weight loss is by altering the digestive process. The medication slows down the rate at which food leaves the stomach, resulting in a prolonged sensation of fullness. This delay in gastric emptying helps individuals feel satiated sooner during meals, thereby reducing the likelihood of overeating.

Additionally, semaglutide has a significant impact on insulin secretion and its efficiency in the body. It enhances the body's ability to use insulin more effectively, promoting the transport of sugar into cells where it can be used for energy, rather than being stored as fat. This optimization of insulin function is particularly beneficial for individuals with type 2 diabetes, as it helps in better glucose management, but it also contributes to weight loss in non-diabetic individuals.

Furthermore, semaglutide acts by mimicking the effects of a naturally occurring hormone that targets specific areas in the brain responsible for regulating appetite. By stimulating these brain regions, semaglutide effectively reduces the feeling of hunger, leading to a decrease in overall calorie intake. This appetite-suppressing effect is a crucial aspect of how semaglutide contributes to weight management.